The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a statement following the publication of a meta-analysis in the New England Journal of Medicine linking rosiglitazone with cardiovascular events.

The publication of the original paper has already been covered, as has the FDA response to the study.

The MHRA have highlighted that the product information for rosiglitazone has carried warnings about heart failure since 2000 and myocardial infarction since 2006.

The MHRA advice is that “patients should not stop treatment with rosiglitazone but should discuss their medication with their doctor at their next routine appointment“.